Tissue expression
Cell line expression
Protein structure
PSMA1
Proteasome 20S subunit alpha 1HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2009]
Top validated antibodies |
|||||
Invitrogen Antibodies | PA1-963 | 1 references | Polyclonal |
WB
ICC
IP
OA |
|
Proteintech Group | 11175-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | H00005682-M01 | 1 references | Monoclonal |
WB
EL
ICC
BN |
|
Boster Biological Technology | A07591 | Polyclonal |
WB
ICC
IP
IHC
FC
|
||
Cusabio Biotech Co., Ltd | CSB-PA018865LA01HU | Polyclonal |
WB
EL
ICC
IP
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider