Tissue expression
Cell line expression
Protein structure
PRICKLE1
Prickle planar cell polarity protein 1EPM1B, FLJ31937, RILP
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| Proteintech Group | 7 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| Invitrogen Antibodies | 1 references | Polyclonal |
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| Boster Biological Technology | Polyclonal |
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| NovoPro Bioscience Inc. | Polyclonal |
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