Tissue expression
Cell line expression
Protein structure

HLA-DRB5

Major histocompatibility complex, class II, DR beta 5
 
HLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene. [provided by RefSeq, Feb 2020]
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207 antibodies from 23 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
82 antibodies
antibodies-online
40 antibodies
Proteintech Group
1 antibody
Aviva Systems Biology
1 antibody
FineTest Biotech
1 antibody
NovoPro Bioscience Inc.
1 antibody
OriGene
3 antibodies
Abnova Corporation
6 antibodies
Novus Biologicals
2 antibodies
Abgent
1 antibody
Acris Antibodies GmbH
1 antibody
GeneTex
5 antibodies
St John's Laboratory
2 antibodies
MyBioSource
2 antibodies
ProSci
1 antibody
Creative Biolabs
5 antibodies
United States Biological
15 antibodies
Creative Diagnostics
2 antibodies
GenWay
2 antibodies
Leading Biology
1 antibody
Abbexa
1 antibody
MilliporeSigma / Merck KGaA
1 antibody