Tissue expression
Cell line expression
Protein structure

SPEN

Spen family transcriptional repressor
KIAA0929, MINT, RBM15C, SHARP 
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
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59 antibodies from 19 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
Invitrogen Antibodies
6 antibodies
antibodies-online
11 antibodies
Abnova Corporation
2 antibodies
Atlas Antibodies
2 antibodies
Biorbyt
5 antibodies
Bethyl Laboratories
2 antibodies
Everest Biotech
1 antibody
MilliporeSigma / Merck KGaA
2 antibodies
St John's Laboratory
1 antibody
LSBio
3 antibodies
Aviva Systems Biology
1 antibody
GeneTex
1 antibody
MyBioSource
1 antibody
United States Biological
12 antibodies
Abgent
1 antibody
Creative Diagnostics
1 antibody
Leading Biology
1 antibody
ProSci
1 antibody