Tissue expression
Cell line expression
Protein structure
XRCC3
X-ray repair cross complementing 3This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio | Polyclonal |
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| Novus Biologicals | 12 references | Polyclonal |
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| antibodies-online | 1 references | Polyclonal |
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| GeneTex | 2 references | Monoclonal |
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| Proteintech Group | 3 references | Polyclonal |
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