GSAP

gene product
LOC54103, PION
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]). [supplied by OMIM, Nov 2010]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
175 antibodies from 21 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
1 antibody
Arigo
1 antibody
antibodies-online
49 antibodies
LifeSpan BioSciences, Inc.
52 antibodies
OriGene
3 antibodies
Invitrogen Antibodies
1 antibody
Biorbyt
3 antibodies
Abgent
2 antibodies
ProSci
1 antibody
Acris Antibodies GmbH
3 antibodies
Novus Biologicals
27 antibodies
Abnova Corporation
4 antibodies
Aviva Systems Biology
2 antibodies
R&D Systems
1 antibody
MyBioSource
4 antibodies
Boster Biological Technology
1 antibody
United States Biological
14 antibodies
Sigma-Aldrich
2 antibodies
Abbiotec
1 antibody
Creative Diagnostics
2 antibodies
Rockland Immunochemicals, Inc.
1 antibody