Tissue expression
Cell line expression
Protein structure
CHRNA3
Cholinergic receptor nicotinic alpha 3 subunitThis locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
Top validated antibodies |
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Invitrogen Antibodies | MA5-31685 | 1 references | Monoclonal |
WB
EL
ICC
FC |
|
antibodies-online | ABIN5681689 | Monoclonal |
WB
EL
ICC
IHC
FC
|
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Novus Biologicals | NBP2-61673 | Monoclonal |
WB
EL
ICC
FC |
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Proteintech Group | 10333-1-AP | Polyclonal |
WB
EL
IHC
FC |
||
NovoPro Bioscience Inc. | 109279 | Polyclonal |
WB
EL
IHC
FC |
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