RPS6KB2

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jul 2008]

Description

ribosomal protein S6 kinase, 70kDa, polypeptide 2

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

11:q13.2 (67428460 - 67435408)

Ensembl ID

ENSG00000175634  (ver. 84.38)

Orthologs

Mouse Rps6kb2: ENSMUSG00000024830

UniProt

Q9UBS0

neXtProt

NX_Q9UBS0

Human splice variants
Mouse splice variants