CCL1

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014]

Description

C-C motif chemokine ligand 1

Tissue specificity

Tissue enhanced (intestine, lymphoid tissue)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

17:q12 (34360328 - 34363233)

Ensembl ID

ENSG00000108702  (ver. 103.38)

Orthologs

-

UniProt

P22362

neXtProt

NX_P22362

Human splice variants