POU1F1

This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

POU class 1 homeobox 1

Tissue specificity

Tissue enriched (pituitary gland)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

3 (87259404 - 87276584)

Ensembl ID

ENSG00000064835  (ver. 103.38)

Orthologs

Mouse Pou1f1: ENSMUSG00000004842

UniProt

P28069

neXtProt

NX_P28069

Human splice variants
Mouse splice variants

Protein structure