NUDT1

gene product
MTH1
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008]
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211 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
16 antibodies
antibodies-online
78 antibodies
LifeSpan BioSciences, Inc.
25 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
GeneTex
2 antibodies
Invitrogen Antibodies
2 antibodies
Proteintech Group
1 antibody
St John's Laboratory
3 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
8 antibodies
OriGene
3 antibodies
Biorbyt
11 antibodies
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abgent
1 antibody
Cell Signaling Technology, Inc
1 antibody
MyBioSource
3 antibodies
Aviva Systems Biology
1 antibody
Boster Biological Technology
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
38 antibodies
Sigma-Aldrich
2 antibodies
Abbiotec
1 antibody
Abbexa
3 antibodies
Creative Biolabs
1 antibody
Creative Diagnostics
1 antibody
Acris Antibodies GmbH
2 antibodies