Tissue expression
Cell line expression
Protein structure
POU2F3
POU class 2 homeobox 3Epoc-1, OCT11, PLA-1, Skn-1a
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Atlas Antibodies | ![]() |
14 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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