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Protein structure
HSPB8
Heat shock protein family B (small) member 8CMT2L, E2IG1, H11, HSP22
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  15287-1-AP |
9 references | Polyclonal |
WB
EL
ICC
IHC
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| Atlas Antibodies | HPA015876 |
2 references | Polyclonal |
WB
ICC
IHC
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| LSBio | LS-B10221 |
Polyclonal |
WB
ICC
IHC
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| NSJ Bioreagents | R32797 |
Polyclonal |
WB
ICC
IP
IHC
FC
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| Invitrogen Antibodies | H00026353-M04 |
Monoclonal |
WB
EL
IHC
OA
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