KIFAP3

gene product
FLA3, KAP-1, KAP3, SMAP
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
138 antibodies from 21 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
antibodies-online
62 antibodies
NovoPro Bioscience Inc.
2 antibodies
Biorbyt
12 antibodies
RabMAbs
4 antibodies
GeneTex
2 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
17 antibodies
Invitrogen Antibodies
4 antibodies
Abnova Corporation
3 antibodies
Atlas Antibodies
2 antibodies
Aviva Systems Biology
2 antibodies
Novus Biologicals
2 antibodies
OriGene
2 antibodies
MyBioSource
2 antibodies
Boster Biological Technology
1 antibody
Creative Biolabs
1 antibody
St John's Laboratory
1 antibody
United States Biological
12 antibodies
Sigma-Aldrich
2 antibodies
Abgent
2 antibodies