Tissue expression
Cell line expression

LEFTY2

gene product
EBAF, LEFTA, LEFTYA, TGFB4 
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
299 antibodies from 35 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
62 antibodies
NovoPro Bioscience Inc.
4 antibodies
Invitrogen Antibodies
10 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
antibodies-online
80 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Biorbyt
14 antibodies
Abnova Corporation
8 antibodies
Acris Antibodies GmbH
5 antibodies
Affinity Biosciences
1 antibody
OriGene
4 antibodies
Aviva Systems Biology
4 antibodies
GeneTex
3 antibodies
St John's Laboratory
5 antibodies
R&D Systems
5 antibodies
Novus Biologicals
5 antibodies
ProSci
2 antibodies
RabMAbs
3 antibodies
Arigo
1 antibody
MyBioSource
8 antibodies
Abbexa
5 antibodies
GenWay
3 antibodies
RayBiotech, Inc.
2 antibodies
Creative Biolabs
17 antibodies
Boster Biological Technology
1 antibody
Signalway Antibody LLC
1 antibody
United States Biological
17 antibodies
Creative Diagnostics
3 antibodies
Leading Biology
3 antibodies
Abgent
1 antibody
MilliporeSigma / Merck KGaA
2 antibodies
EMD Millipore
1 antibody
Rockland Immunochemicals, Inc.
1 antibody