Tissue expression
Cell line expression

PEX5

gene product
PTS1R, PXR1 
The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
More gene data

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285 antibodies from 31 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
5 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
20 antibodies
Novus Biologicals
7 antibodies
NovoPro Bioscience Inc.
2 antibodies
GeneTex
7 antibodies
Acris Antibodies GmbH
1 antibody
OriGene
16 antibodies
Abnova Corporation
2 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
antibodies-online
94 antibodies
LifeSpan BioSciences, Inc.
31 antibodies
Cusabio Biotech Co., Ltd
6 antibodies
Affinity Biosciences
1 antibody
Boster Biological Technology
1 antibody
Biorbyt
12 antibodies
Aviva Systems Biology
3 antibodies
Bioworld Technology, Inc
1 antibody
Creative Diagnostics
6 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Abbexa
10 antibodies
MyBioSource
6 antibodies
Cell Signaling Technology, Inc
1 antibody
ProSci
1 antibody
United States Biological
24 antibodies
Leading Biology
1 antibody
Creative Biolabs
4 antibodies
MilliporeSigma / Merck KGaA
2 antibodies