NSFL1C

N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011]

Description

NSFL1 (p97) cofactor (p47)

Protein family

Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

20:p13 (1442162 - 1473842)

Ensembl ID

ENSG00000088833  (ver. 84.38)

Orthologs

Mouse Nsfl1c: ENSMUSG00000027455

UniProt

Q9UNZ2

neXtProt

NX_Q9UNZ2

Human splice variants
Mouse splice variants