Tissue expression
Cell line expression
Protein structure
PRAME
PRAME nuclear receptor transcriptional regulatorCT130, MAPE
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Aviva Systems Biology | ![]() |
Polyclonal |
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Abbexa | ![]() |
Polyclonal |
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