DSC1

gene product
CDHF1
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
231 antibodies from 26 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
10 antibodies
R&D Systems
8 antibodies
antibodies-online
72 antibodies
Biorbyt
22 antibodies
Atlas Antibodies
2 antibodies
GeneTex
2 antibodies
Abgent
1 antibody
Arigo
1 antibody
Aviva Systems Biology
1 antibody
LifeSpan BioSciences, Inc.
43 antibodies
Progen Biotechnik GmbH
2 antibodies
Invitrogen Antibodies
4 antibodies
Abnova Corporation
3 antibodies
Acris Antibodies GmbH
3 antibodies
Sigma-Aldrich
1 antibody
ProSci
1 antibody
Creative Biolabs
18 antibodies
MyBioSource
4 antibodies
OriGene
3 antibodies
St John's Laboratory
1 antibody
United States Biological
12 antibodies
Creative Diagnostics
2 antibodies
GenWay
1 antibody
Abbexa
1 antibody
RabMAbs
1 antibody