Tissue expression
Cell line expression
Protein structure
UPB1
Beta-ureidopropionase 1BUP1
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Atlas Antibodies | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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Abnova Corporation | ![]() |
Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
Polyclonal |
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