KCNJ12

This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Description

Potassium inwardly rectifying channel subfamily J member 12

Tissue specificity

Group enriched (brain, skeletal muscle, tongue)

Subcell location

Nucleoplasm, Golgi apparatus, Cytosol

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters
Voltage-gated ion channels

Chromosome

17:p11.2 (21376357 - 21419870)

Ensembl ID

ENSG00000184185  (ver. 103.38)

Orthologs

-

UniProt

Q14500

neXtProt

NX_Q14500

Human splice variants