Tissue expression
Cell line expression
Protein structure
MANEA
Mannosidase endo-alphaFLJ12838, mandaselin
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]). [supplied by OMIM, Sep 2008]
Top validated antibodies |
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Proteintech Group | 21296-1-AP | Polyclonal |
WB
EL
ICC
IHC |
||
Atlas Antibodies | HPA011046 | Polyclonal |
ICC
IHC |
||
Invitrogen Antibodies | 21296-1-AP | Polyclonal |
WB
ICC
IHC
|
||
NovoPro Bioscience Inc. | 112467 | Polyclonal |
WB
EL
ICC
|
||
Biorbyt | orb451396 | Polyclonal |
EL
ICC
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider