Tissue expression
Cell line expression
Protein structure
DLK1
Delta like non-canonical Notch ligand 1Delta1, FA1, pG2, Pref-1, ZOG
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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antibodies-online | ABIN969086 | 2 references | Monoclonal |
WB
EL
ICC
FC |
|
Invitrogen Antibodies | MA5-15915 | 1 references | Monoclonal |
WB
EL
ICC
FC
OA
|
|
GeneTex | GTX60309 | Polyclonal |
WB
EL
ICC
IP
IHC
FC |
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Proteintech Group | 10636-1-AP | 21 references | Polyclonal |
WB
EL
IHC
|
|
R&D Systems | MAB1144-100 | 4 references | Monoclonal |
WB
ICC
FC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider