ARHGEF1

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

Description

Rho guanine nucleotide exchange factor 1

Protein family

Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

19:q13.2 (41883161 - 41930150)

Ensembl ID

ENSG00000076928  (ver. 84.38)

Orthologs

Mouse Arhgef1: ENSMUSG00000040940

UniProt

Q92888

neXtProt

NX_Q92888

Human splice variants
Mouse splice variants