FBXL6

This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Description

F-box and leucine rich repeat protein 6

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

8 (144355431 - 144359376)

Ensembl ID

ENSG00000182325  (ver. 103.38)

Orthologs

Mouse Fbxl6: ENSMUSG00000022559

UniProt

Q8N531

neXtProt

NX_Q8N531

Human splice variants
Mouse splice variants

Protein structure