PDE3A

gene product
CGI-PDE
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
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Eligible for validation within AVI
208 antibodies from 30 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Novus Biologicals
11 antibodies
antibodies-online
57 antibodies
GeneTex
3 antibodies
Abnova Corporation
8 antibodies
Acris Antibodies GmbH
8 antibodies
Affinity Biosciences
2 antibodies
Bethyl Laboratories
2 antibodies
FabGennix
9 antibodies
NovoPro Bioscience Inc.
3 antibodies
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Biorbyt
8 antibodies
LifeSpan BioSciences, Inc.
31 antibodies
OriGene
7 antibodies
Invitrogen Antibodies
6 antibodies
Aviva Systems Biology
2 antibodies
ProSci
3 antibodies
Creative Diagnostics
3 antibodies
Boster Biological Technology
1 antibody
United States Biological
19 antibodies
MyBioSource
5 antibodies
Sigma-Aldrich
3 antibodies
Creative Biolabs
2 antibodies
EMD Millipore
1 antibody
RabMAbs
1 antibody
St John's Laboratory
1 antibody
Exalpha Biologicals, Inc.
3 antibodies
RayBiotech, Inc.
3 antibodies
GenWay
1 antibody