Tissue expression
Cell line expression

PSMB8

gene product
beta5i, D6S216E, LMP7, PSMB5i, RING10 
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit. [provided by RefSeq, Jul 2008]
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419 antibodies from 41 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
Novus Biologicals
11 antibodies
Abnova Corporation
10 antibodies
antibodies-online
110 antibodies
Invitrogen Antibodies
17 antibodies
LifeSpan BioSciences, Inc.
69 antibodies
NovoPro Bioscience Inc.
1 antibody
GeneTex
4 antibodies
Biorbyt
31 antibodies
OriGene
5 antibodies
Acris Antibodies GmbH
6 antibodies
Abgent
2 antibodies
Enzo Life Sciences
5 antibodies
Boster Biological Technology
3 antibodies
Atlas Antibodies
2 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Aviva Systems Biology
4 antibodies
Affinity Biosciences
1 antibody
HUABIO Research
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
St John's Laboratory
4 antibodies
Signalway Antibody LLC
1 antibody
Cell Signaling Technology, Inc
2 antibodies
Bethyl Laboratories
2 antibodies
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
Creative Diagnostics
3 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
RabMAbs
1 antibody
MyBioSource
9 antibodies
R&D Systems
2 antibodies
Abbexa
10 antibodies
Leading Biology
3 antibodies
Arigo
1 antibody
United States Biological
43 antibodies
Creative Biolabs
14 antibodies
MilliporeSigma / Merck KGaA
1 antibody
ProSci
1 antibody
EMD Millipore
1 antibody