VSIG1

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Description

V-set and immunoglobulin domain containing 1

Tissue specificity

Tissue enriched (stomach)

Subcell location

Vesicles, Cytosol

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

X (108044970 - 108079184)

Ensembl ID

ENSG00000101842  (ver. 103.38)

Orthologs

Mouse Vsig1: ENSMUSG00000031430

UniProt

Q86XK7

neXtProt

NX_Q86XK7

Human splice variants
Mouse splice variants

Protein structure