Tissue expression
Cell line expression
Protein structure
SPANXC
SPANX family member CCT11.3, CTp11
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX85700 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP1-03285 | Polyclonal |
WB
EL
ICC
IHC |
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Abnova Corporation | PAB11268 | 3 references | Polyclonal |
WB
IHC |
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Biorbyt | orb1249762 | Polyclonal |
WB
EL
ICC
IHC |
||
antibodies-online | ABIN2026128 | Polyclonal |
WB
EL
ICC
IHC |
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