Tissue expression
Cell line expression
Protein structure

ISCU

Iron-sulfur cluster assembly enzyme
hnifU, ISU2, NIFUN 
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. [provided by RefSeq, Feb 2016]
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293 antibodies from 28 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
Invitrogen Antibodies
14 antibodies
Novus Biologicals
30 antibodies
Abnova Corporation
4 antibodies
antibodies-online
73 antibodies
Biorbyt
27 antibodies
NovoPro Bioscience Inc.
3 antibodies
FineTest Biotech
1 antibody
Cusabio Biotech Co., Ltd
6 antibodies
GeneTex
2 antibodies
Abgent
2 antibodies
Affinity Biosciences
1 antibody
Atlas Antibodies
2 antibodies
OriGene
16 antibodies
United States Biological
33 antibodies
Aviva Systems Biology
3 antibodies
St John's Laboratory
2 antibodies
MyBioSource
4 antibodies
Creative Diagnostics
3 antibodies
Boster Biological Technology
1 antibody
ProSci
1 antibody
RayBiotech, Inc.
1 antibody
Creative Biolabs
5 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Leading Biology
2 antibodies
Abbexa
9 antibodies
Acris Antibodies GmbH
2 antibodies