Tissue expression
Cell line expression
Protein structure
UBE2M
Ubiquitin conjugating enzyme E2 MhUbc12, UBC12
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
8 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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