PAPPA

gene product
ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
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842 antibodies from 28 providers.

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antibodies-online
322 antibodies
Novus Biologicals
211 antibodies
NSJ Bioreagents
6 antibodies
R&D Systems
2 antibodies
GeneTex
18 antibodies
LifeSpan BioSciences, Inc.
148 antibodies
NovoPro Bioscience Inc.
2 antibodies
Atlas Antibodies
1 antibody
Biorbyt
15 antibodies
Invitrogen Antibodies
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
ABEOMICS Inc.
2 antibodies
Creative Biolabs
21 antibodies
Abnova Corporation
14 antibodies
OriGene
1 antibody
MyBioSource
8 antibodies
Creative Diagnostics
7 antibodies
Aviva Systems Biology
12 antibodies
Abgent
1 antibody
GenWay
18 antibodies
Abbexa
3 antibodies
Arigo
3 antibodies
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3 antibodies
Sigma-Aldrich
2 antibodies
St John's Laboratory
1 antibody
United States Biological
1 antibody