WT1

gene product
AWT1, GUD, WAGR, WIT-2
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
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1035 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
503 antibodies
Biorbyt
40 antibodies
NSJ Bioreagents
10 antibodies
Invitrogen Antibodies
6 antibodies
Novus Biologicals
152 antibodies
Abgent
6 antibodies
GeneTex
13 antibodies
OriGene
14 antibodies
Acris Antibodies GmbH
10 antibodies
Boster Biological Technology
3 antibodies
R&D Systems
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
Aviva Systems Biology
6 antibodies
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
Signalway Antibody LLC
1 antibody
LifeSpan BioSciences, Inc.
123 antibodies