BAG5

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

BAG cochaperone 5

Tissue specificity

Tissue enriched (testis)

Subcell location

Vesicles

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14:q32.33 (103556545 - 103562657)

Ensembl ID

ENSG00000166170  (ver. 103.38)

Orthologs

Mouse Bag5: ENSMUSG00000049792

UniProt

Q9UL15

neXtProt

NX_Q9UL15

Human splice variants
Mouse splice variants