BCAR1

gene product
CAS, CASS1, Crkas, P130Cas
The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
More gene data

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
795 antibodies from 38 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
2 antibodies
OriGene
25 antibodies
Invitrogen Antibodies
23 antibodies
GeneTex
7 antibodies
Novus Biologicals
38 antibodies
antibodies-online
261 antibodies
Cell Signaling Technology, Inc
6 antibodies
NovoPro Bioscience Inc.
5 antibodies
Abnova Corporation
10 antibodies
LifeSpan BioSciences, Inc.
114 antibodies
Affinity Biosciences
9 antibodies
Biorbyt
38 antibodies
Enzo Life Sciences
1 antibody
Aviva Systems Biology
5 antibodies
Acris Antibodies GmbH
11 antibodies
Bethyl Laboratories
3 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Abgent
4 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
5 antibodies
St John's Laboratory
9 antibodies
ProSci
2 antibodies
Creative Biolabs
21 antibodies
Abbkine Scientific Co.Ltd.
5 antibodies
MyBioSource
12 antibodies
R&D Systems
2 antibodies
RabMAbs
5 antibodies
United States Biological
74 antibodies
Abbexa
19 antibodies
Creative Diagnostics
9 antibodies
GenWay
2 antibodies
Leading Biology
3 antibodies
EMD Millipore
1 antibody
Everest Biotech
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
2 antibodies