DFFA

gene product
DFF-45, DFF1, DFF45, ICAD
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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773 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
antibodies-online
247 antibodies
Novus Biologicals
15 antibodies
GeneTex
21 antibodies
NovoPro Bioscience Inc.
1 antibody
Biorbyt
26 antibodies
Abnova Corporation
20 antibodies
OriGene
32 antibodies
LifeSpan BioSciences, Inc.
160 antibodies
Rockland Immunochemicals, Inc.
4 antibodies
Enzo Life Sciences
2 antibodies
Bioworld Technology, Inc
2 antibodies
Acris Antibodies GmbH
31 antibodies
ProSci
5 antibodies
Bethyl Laboratories
3 antibodies
Abgent
11 antibodies
Aviva Systems Biology
13 antibodies
Arigo
6 antibodies
Atlas Antibodies
3 antibodies
Invitrogen Antibodies
13 antibodies
R&D Systems
2 antibodies
RabMAbs
7 antibodies
St John's Laboratory
5 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Boster Biological Technology
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Affinity Biosciences
1 antibody
MyBioSource
18 antibodies
ABEOMICS Inc.
2 antibodies
NSJ Bioreagents
1 antibody
United States Biological
66 antibodies
Spring Bioscience
4 antibodies
RayBiotech, Inc.
4 antibodies
Abbiotec
3 antibodies
GenWay
11 antibodies
Sigma-Aldrich
8 antibodies
Creative Diagnostics
3 antibodies
EMD Millipore
3 antibodies