Tissue expression
Cell line expression

ANPEP

gene product
CD13, gp150, LAP1, p150, PEPN 
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
1953 antibodies from 47 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
9 antibodies
R&D Systems
10 antibodies
Novus Biologicals
172 antibodies
GeneTex
21 antibodies
antibodies-online
662 antibodies
OriGene
62 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
64 antibodies
Cell Signaling Technology, Inc
2 antibodies
Acris Antibodies GmbH
57 antibodies
Biorbyt
87 antibodies
NSJ Bioreagents
9 antibodies
Boster Biological Technology
9 antibodies
HUABIO Research
3 antibodies
LifeSpan BioSciences, Inc.
293 antibodies
NovoPro Bioscience Inc.
12 antibodies
Cusabio Biotech Co., Ltd
9 antibodies
Abnova Corporation
15 antibodies
BioLegend
30 antibodies
Sino Biological Inc.
7 antibodies
Antibodies.com
10 antibodies
Wuhan Fine Biotech Co., Ltd.
2 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
17 antibodies
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
RabMAbs
5 antibodies
Creative Biolabs
92 antibodies
Abgent
9 antibodies
ABEOMICS Inc.
4 antibodies
Creative Diagnostics
21 antibodies
GenWay
17 antibodies
Miltenyi Biotec
18 antibodies
Leading Biology
16 antibodies
Absolute Antibody
6 antibodies
Abbexa
38 antibodies
MyBioSource
11 antibodies
ProSci
5 antibodies
United States Biological
69 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
Abiocode, Inc.
1 antibody
Abbiotec
2 antibodies
eBioscience, An Affymetrix Company
25 antibodies
Exalpha Biologicals, Inc.
6 antibodies
EMD Millipore
1 antibody