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Protein structure
MAP3K1
Mitogen-activated protein kinase kinase kinase 1MAPKKK1, MEKK, MEKK1
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
Top validated antibodies |
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| Proteintech Group |  19970-1-AP |
10 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C199217 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-79629 |
1 references | Polyclonal |
WB
IHC
OA
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| Novus Biologicals | NBP2-47810-0.1mg |
Monoclonal |
WB
ICC
IHC
FC
|
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| Affinity Biosciences | DF8741 |
Polyclonal |
WB
EL
ICC
IHC
|
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