ARNT2

gene product
bHLHe1, KIAA0307
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]
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1 antibody
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1 antibody
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1 antibody
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1 antibody
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Abnova Corporation
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1 antibody
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1 antibody
Boster Biological Technology
1 antibody
St John's Laboratory
1 antibody
United States Biological
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Creative Diagnostics
3 antibodies
Creative Biolabs
1 antibody
Sigma-Aldrich
1 antibody