DAB2

gene product
DOC-2
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
299 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Proteintech Group
1 antibody
Invitrogen Antibodies
5 antibodies
antibodies-online
97 antibodies
Atlas Antibodies
1 antibody
Novus Biologicals
8 antibodies
NovoPro Bioscience Inc.
4 antibodies
Aviva Systems Biology
4 antibodies
Santa Cruz Biotechnology
1 antibody
R&D Systems
2 antibodies
Biorbyt
12 antibodies
Abgent
9 antibodies
LifeSpan BioSciences, Inc.
38 antibodies
Cell Signaling Technology, Inc
2 antibodies
St John's Laboratory
1 antibody
Abnova Corporation
5 antibodies
GeneTex
1 antibody
OriGene
1 antibody
ProSci
1 antibody
RabMAbs
4 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Everest Biotech
2 antibodies
Acris Antibodies GmbH
1 antibody
Creative Biolabs
8 antibodies
MyBioSource
5 antibodies
Creative Diagnostics
4 antibodies
RayBiotech, Inc.
3 antibodies
United States Biological
39 antibodies
Leading Biology
8 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
2 antibodies