CAST

gene product
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
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Antibodies

 

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Antibodypedia Validation Initiative

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Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
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Validated within AVI
Eligible for validation within AVI
350 antibodies from 29 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
NovoPro Bioscience Inc.
2 antibodies
Proteintech Group
1 antibody
Invitrogen Antibodies
5 antibodies
antibodies-online
133 antibodies
Novus Biologicals
32 antibodies
OriGene
9 antibodies
Abnova Corporation
9 antibodies
Boster Biological Technology
2 antibodies
NSJ Bioreagents
1 antibody
Santa Cruz Biotechnology
1 antibody
GeneTex
7 antibodies
LifeSpan BioSciences, Inc.
41 antibodies
Cell Signaling Technology, Inc
1 antibody
Atlas Antibodies
2 antibodies
Biorbyt
16 antibodies
Acris Antibodies GmbH
9 antibodies
Bethyl Laboratories
3 antibodies
St John's Laboratory
3 antibodies
Arigo
5 antibodies
Spring Bioscience
8 antibodies
Sigma-Aldrich
5 antibodies
MyBioSource
8 antibodies
Creative Diagnostics
3 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody
United States Biological
12 antibodies
Abbexa
3 antibodies
GenWay
2 antibodies