Tissue expression
Cell line expression
Protein structure
EDNRB
Endothelin receptor type BETB, HSCR, HSCR2
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Top validated antibodies |
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Proteintech Group | 20964-1-AP | 3 references | Polyclonal |
WB
EL
IHC
FC |
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Invitrogen Antibodies | PA3-066 | 4 references | Polyclonal |
WB
ICC
IHC
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antibodies-online | ABIN2841017 | 1 references | Polyclonal |
WB
ICC
IHC
FC |
|
Abgent | AP6789B | Polyclonal |
WB
ICC
IHC
FC |
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GeneTex | GTX17408 | Polyclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider