CHM

gene product
DXS540, REP-1, TCD
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
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117 antibodies from 27 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
24 antibodies
Invitrogen Antibodies
2 antibodies
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Boster Biological Technology
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1 antibody
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NSJ Bioreagents
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SICGEN
4 antibodies
Acris Antibodies GmbH
2 antibodies
Aviva Systems Biology
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GeneTex
2 antibodies
Novus Biologicals
2 antibodies
Abgent
1 antibody
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
OriGene
1 antibody
Santa Cruz Biotechnology
1 antibody
St John's Laboratory
5 antibodies
Abbexa
4 antibodies
Creative Biolabs
1 antibody
EMD Millipore
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
1 antibody
United States Biological
13 antibodies
MyBioSource
1 antibody
ProSci
1 antibody