PFKFB1

gene product
PFRX
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
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AntibodyRefsTypeWBELICCIPIHCFC
Abnova Corporation
7 antibodies
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1 antibody
Invitrogen Antibodies
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RabMAbs
1 antibody
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Sigma-Aldrich
1 antibody