Tissue expression
Cell line expression
Protein structure
GAB2
GRB2 associated binding protein 2KIAA0571
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
Top validated antibodies |
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Proteintech Group | 22549-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | PA5-119921 | Polyclonal |
WB
ICC
IHC
FC |
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antibodies-online | ABIN1881358 | 2 references | Polyclonal |
WB
FC |
|
Bioss | bs-3177R | 1 references | Polyclonal |
WB
ICC
IHC
|
|
LSBio | LS-C198988 | Polyclonal |
WB
EL
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider