Tissue expression
Cell line expression
Protein structure
TECPR2
Tectonin beta-propeller repeat containing 2KIAA0329
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Top validated antibodies |
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Atlas Antibodies | HPA000658 | 1 references | Polyclonal |
ICC
IHC |
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Novus Biologicals | NBP1-93642 | 1 references | Polyclonal |
ICC
IHC |
|
Cusabio Biotech Co., Ltd | CSB-PA023369LA01HU | Polyclonal |
EL
ICC
IHC
|
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Biorbyt | orb2214885 | Polyclonal |
EL
ICC
IHC
|
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LSBio | LS-C499906 | Polyclonal |
EL
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider