Tissue expression
Cell line expression
Protein structure
OXT
Oxytocin/neurophysin I prepropeptideOT, OT-NPI, OXT-NPI
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]
Top validated antibodies |
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antibodies-online | ABIN953964 | 4 references | Polyclonal |
WB
IHC
FC
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Invitrogen Antibodies | PA5-26701 | 1 references | Polyclonal |
WB
IHC
FC
|
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Acris Antibodies GmbH | AP52854PU-N | Polyclonal |
WB
IHC
FC
|
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OriGene | AP52854PU-N | Polyclonal |
WB
IHC
FC
|
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Cusabio Biotech Co., Ltd | CSB-PA017315LA01HU | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider