Tissue expression
Cell line expression
Protein structure
CHD8
Chromodomain helicase DNA binding protein 8DUPLIN, HELSNF1, KIAA1564
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
Top validated antibodies |
|||||
Novus Biologicals | NB100-60417 | 3 references | Polyclonal |
WB
IP
IHC
ChIP |
|
antibodies-online | ABIN253035 | 2 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
|
|
Invitrogen Antibodies | A301-224A | Polyclonal |
WB
IP
IHC
OA |
||
LSBio | LS-C288034 | Polyclonal |
WB
IP
IHC
|
||
Biorbyt | orb1743825 | Polyclonal |
WB
EL
IHC
FC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider