TFPI

gene product
EPI, LACI, TFI, TFPI1
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
648 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
GeneTex
7 antibodies
OriGene
20 antibodies
LifeSpan BioSciences, Inc.
133 antibodies
Novus Biologicals
35 antibodies
Biorbyt
29 antibodies
R&D Systems
6 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
8 antibodies
antibodies-online
183 antibodies
Bioworld Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
NovoPro Bioscience Inc.
11 antibodies
ProSci
3 antibodies
Abgent
4 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
11 antibodies
Aviva Systems Biology
4 antibodies
Creative Biolabs
93 antibodies
Boster Biological Technology
3 antibodies
Acris Antibodies GmbH
3 antibodies
St John's Laboratory
4 antibodies
Antibodies.com
1 antibody
Proteintech Group
1 antibody
NSJ Bioreagents
3 antibodies
Everest Biotech
1 antibody
MyBioSource
8 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Arigo
1 antibody
United States Biological
28 antibodies
Creative Diagnostics
12 antibodies
Sino Biological Inc.
9 antibodies
RayBiotech, Inc.
3 antibodies
Molecular Innovations
2 antibodies
GenWay
2 antibodies
Sigma-Aldrich
2 antibodies
RabMAbs
1 antibody