RBP4

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]

Description

retinol binding protein 4

Protein family

Cancer-related genes, Disease related genes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

10:q23.33 (93591687 - 93601744)

Ensembl ID

ENSG00000138207  (ver. 84.38)

Orthologs

Mouse Rbp4: ENSMUSG00000024990

UniProt

P02753

neXtProt

NX_P02753

Human splice variants
Mouse splice variants